A controlled 6-month clinical trial to study the effects of a stannous fluoride dentifrice on gingivitis
Objectives: This study was conducted to assess anti-plaque and anti-gingivitis benefits of a stabilized stannous fluoride (SnF2)/sodium hexametaphosphate (SHMP) dentifrice versus a negative control. Material and Methods: This was a randomized, 6-month, stratified, single-centre, double-blind, pa...
| Main Author: | Mark Mallatt |
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| Format: | Koleksi Audio Visual |
| Language: | Bahasa Inggris |
| Published: |
Blackwell Synergy
2007
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| Subjects: | |
| Online Access: |
http://oaipmh-jogjalib.umy.ac.idkatalog.php?opo=lihatDetilKatalog&id=93640 |
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oai:lib.umy.ac.id:93640 |
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oai_dc |
| spelling |
oai:lib.umy.ac.id:936402021-06-16T13:12:39ZA controlled 6-month clinical trial to study the effects of a stannous fluoride dentifrice on gingivitisMark Mallatt Objectives: This study was conducted to assess anti-plaque and anti-gingivitis benefits of a stabilized stannous fluoride (SnF2)/sodium hexametaphosphate (SHMP) dentifrice versus a negative control. Material and Methods: This was a randomized, 6-month, stratified, single-centre, double-blind, parallel group, clinical study conducted in harmony with the guidelines for evaluating chemotherapeutic products for the control of gingivitis outlined by the American Dental Association. A stabilized 0.454% SnF2/SHMP dentifrice was tested against a commercially available negative control dentifrice. Following baseline measurements, subjects received a dental prophylaxis. Subjects were instructed to brush twice daily for 60 s using their assigned product. Efficacy measurements were obtained at baseline, 3 and 6 months post treatment using the Modified Gingival Index, Gingival Bleeding Index and the Turesky Modified Quigley-Hein Plaque Index. Oral tissue examinations were performed at all visits. Results: A total of 140 subjects were enroled and 128 completed the study. Results after 6 months showed the SnF2 dentifrice delivered a 16.9% reduction in gingivitis (po0.001), a 40.8% reduction (po0.001) in gingival bleeding, and an 8.5% reduction in plaque (p50.001) versus the negative control. Both treatments were well tolerated. Conclusions: Twice daily use of the SnF2/SHMP dentifrice over 6 months provided statistically significant anti-plaque and anti-gingivitis benefits relative to a negative control.Blackwell Synergy2007Koleksi Audio Visual Bahasa Inggrishttp://oaipmh-jogjalib.umy.ac.idkatalog.php?opo=lihatDetilKatalog&id=93640 |
| institution |
Universitas Muhammadiyah Yogyakarta |
| collection |
Perpustakaan Yogyakarta |
| language |
Bahasa Inggris |
| topic |
|
| spellingShingle |
Mark Mallatt A controlled 6-month clinical trial to study the effects of a stannous fluoride dentifrice on gingivitis |
| description |
Objectives: This study was conducted to assess anti-plaque and anti-gingivitis
benefits of a stabilized stannous fluoride (SnF2)/sodium hexametaphosphate (SHMP)
dentifrice versus a negative control.
Material and Methods: This was a randomized, 6-month, stratified, single-centre,
double-blind, parallel group, clinical study conducted in harmony with the guidelines
for evaluating chemotherapeutic products for the control of gingivitis outlined by the
American Dental Association. A stabilized 0.454% SnF2/SHMP dentifrice was tested
against a commercially available negative control dentifrice. Following baseline
measurements, subjects received a dental prophylaxis. Subjects were instructed to
brush twice daily for 60 s using their assigned product. Efficacy measurements were
obtained at baseline, 3 and 6 months post treatment using the Modified Gingival Index,
Gingival Bleeding Index and the Turesky Modified Quigley-Hein Plaque Index. Oral
tissue examinations were performed at all visits.
Results: A total of 140 subjects were enroled and 128 completed the study. Results
after 6 months showed the SnF2 dentifrice delivered a 16.9% reduction in gingivitis
(po0.001), a 40.8% reduction (po0.001) in gingival bleeding, and an 8.5% reduction
in plaque (p50.001) versus the negative control. Both treatments were well tolerated.
Conclusions: Twice daily use of the SnF2/SHMP dentifrice over 6 months provided
statistically significant anti-plaque and anti-gingivitis benefits relative to a negative
control. |
| format |
Koleksi Audio Visual |
| author |
Mark Mallatt |
| author_sort |
Mark Mallatt |
| title |
A controlled 6-month clinical trial to study the effects of a stannous fluoride dentifrice on gingivitis |
| title_short |
A controlled 6-month clinical trial to study the effects of a stannous fluoride dentifrice on gingivitis |
| title_full |
A controlled 6-month clinical trial to study the effects of a stannous fluoride dentifrice on gingivitis |
| title_fullStr |
A controlled 6-month clinical trial to study the effects of a stannous fluoride dentifrice on gingivitis |
| title_full_unstemmed |
A controlled 6-month clinical trial to study the effects of a stannous fluoride dentifrice on gingivitis |
| title_sort |
controlled 6-month clinical trial to study the effects of a stannous fluoride dentifrice on gingivitis |
| publisher |
Blackwell Synergy |
| publishDate |
2007 |
| url |
http://oaipmh-jogjalib.umy.ac.idkatalog.php?opo=lihatDetilKatalog&id=93640 |
| _version_ |
1702756957860921344 |
| score |
14.79448 |